Research about effect of spray drying conditions on hygroscopicity of spray dry powder of gubi compound's water extract and its mechanism / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 663-668, 2014.
Article
in Zh
| WPRIM
| ID: wpr-300172
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate moisture content and hygroscopicity of spray dry powder of Gubi compound's water extract obtained at different spray drying conditions and laying a foundation for spray drying process of Chinese herbal compound preparation.</p><p><b>METHOD</b>In the paper, on the basis of single-factor experiments, the author choose inlet temperature, liquid density, feed rate, air flow rate as investigated factors.</p><p><b>RESULT</b>The experimental absorption rate-time curve and scanning electron microscopy results showed that under different spray drying conditions the spray-dried powders have different morphology and different adsorption process.</p><p><b>CONCLUSION</b>At different spray-dried conditions, the morphology and water content of the powder is different, these differences lead to differences in the adsorption process, at the appropriate inlet temperature and feed rate with a higher sample density and lower air flow rate, in the experimental system the optimum conditions is inlet temperature of 150 degrees C, feed density of 1.05 g x mL(-1), feed rate of 20 mL x min(-1) air flow rate of 30 m3 x h(-1).</p>
Full text:
1
Index:
WPRIM
Main subject:
Particle Size
/
Powders
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Temperature
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Drugs, Chinese Herbal
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Water
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Chemistry
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Wettability
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Desiccation
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Hydrophobic and Hydrophilic Interactions
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Methods
Language:
Zh
Journal:
China Journal of Chinese Materia Medica
Year:
2014
Type:
Article