Pleiotropic effects of herbs characterized with blood-activating and stasis-resolving functions on angiogenesis / 中国结合医学杂志
Chinese journal of integrative medicine
; (12): 795-800, 2016.
Article
in En
| WPRIM
| ID: wpr-301065
Responsible library:
WPRO
ABSTRACT
Accumulative evidences have underpinned the nature candidates from Chinese medicine (CM), particularly CM served as blood activating and stasis resolving (BASR, Huoxue Huayu in Chinese) by targeting tumor-associated angiogenesis. However, recent experiment research on the therapeutic angiogenesis by BASR-CM attracts wide attention and discussion. This opinion review focused on the underlying link between two indications and anticipated that (1) BASR-CM might emphasize on a balanced multi-cytokines network interaction; (2) BASR-CM might address on the nature of diseases prior to differently affecting physiological and pathological angiogenesis; (3) BASR-CM might mainly act on perivascular cells, either promotes arteriogenesis by increasing arteriogenic factors in ischemic diseases, or simultaneously keep a quiescent vasculature to impede angiogenesis in tumor context.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Blood
/
Drugs, Chinese Herbal
/
Chemistry
/
Angiogenesis Inhibitors
/
Therapeutic Uses
/
Drug Therapy
/
Models, Biological
/
Neovascularization, Pathologic
/
Antineoplastic Agents
Type of study:
Prognostic_studies
Limits:
Animals
/
Humans
Language:
En
Journal:
Chinese journal of integrative medicine
Year:
2016
Type:
Article