A case of rotor syndrome / 대한내과학회지
Korean Journal of Medicine
; : 109-113, 2000.
Article
in Ko
| WPRIM
| ID: wpr-30255
Responsible library:
WPRO
ABSTRACT
Rotor syndrome is a rare benign familial disorder characterized by chronic, fluctuating, nonhemolytic and predominantly conjugated hyperbilirubinemia with normal liver tissue. In contrast to Dubin-Johnson syndrome, there is no liver hyperpigmentation in Rotor syndrome, and BSP clearance does not show a secondary retention peak. The serum bilirubin in patients with Gilbert's syndrome is almost all unconjugated in contrast to Rotor syndrome. A 29-year-old male was admitted due to persistent jaundice. Physical examination revealed icteric sclera without hepatosplenomegaly. Laboratory findings showed increased serum bilirubin with indirect bilirubin predominance. Urinary excretion of total coproporphyrin was markedly elevated, and coproporphyrin I was 66% of total urinary coproporphyrin. Oral cholecystography showed well visualized the gallbladder, but 99mTc-DISIDA scan showed markedly decreased hepatic uptake and poor visualization of the gallbladder and biliary tract. Histology of the liver showed no abnormal finding. We report the case with the review of literature.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Physical Examination
/
Sclera
/
Skin Neoplasms
/
Biliary Tract
/
Bilirubin
/
Cholecystography
/
Survival Rate
/
Hyperpigmentation
/
Technetium Tc 99m Disofenin
/
Gallbladder
Limits:
Adult
/
Humans
/
Male
Language:
Ko
Journal:
Korean Journal of Medicine
Year:
2000
Type:
Article