Hepatitis E virus infection in population of non-remunerate blood donors in Shaoxing / 中华实验和临床病毒学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the incidence of HEV infection in population of non-remunerate blood donors in Shaoxing.</p><p><b>METHODS</b>Blood specimens from 3701 non-remunerate blood donors were collected, ELISA were used to study anti-HEV IgG and IgM antibodies, RT-PCR were further used to study HEV RNA in samples from donors whose anti-HEV IgM was positive.</p><p><b>RESULTS</b>Anti-HEV IgG positive rate was 29.19% (1107/3701), anti-HEV IgM positive rate was 1.35% (50/3701) among non-remunerate blood donors in Shaoxin. Six cases were positive for HEV RNA. The positive rate was 0.16% (6/3701), and all the 6 cases belonged to HEV genotype 1. Different seasons showed no interference on the positive rate of IgG and IgM.</p><p><b>CONCLUSION</b>The detecting and studying of HEV infection among donors was important to ensure the safety of blood products and blood transfusion.</p>