Follicular immunoblastic lymphoma: a clinicopathologic and immunohistochemical study of a case / 南方医科大学学报
Journal of Southern Medical University
; (12): 794-797, 2013.
Article
in En
| WPRIM
| ID: wpr-306465
Responsible library:
WPRO
ABSTRACT
Primary follicular immunoblastic lymphoma (FIBL) is an extremely rare lymphoma. The positive expression of CD10 suggests the lymphoma originating from germinal centers (GC) and CD138-positive expression generally indicates plasmablastic or plasmacytic differentiation. We report such a rare case in a Chinese female patient and analyze the clinicopathologic and immunohistochemical features of this disease. PET-CT examination was performed to detect signs of systemic lymph node metastasis. We also discussed the differential diagnosis of FIBL from follicular lymphoma (FL) and reactive follicular hyperplasia (RFH). As a rare variant of human follicular lymphoma, FIBL is featured by a neoplastic overgrowth of intrafollicular immunoblasts. Compared with FL, FIBL has a greater chance to evolve into diffuse large B-cell lymphoma with therefore a poorer prognosis.
Full text:
1
Index:
WPRIM
Main subject:
Pathology
/
Lymphoma, Follicular
/
Immunoblastic Lymphadenopathy
Type of study:
Prognostic_studies
Limits:
Adult
/
Female
/
Humans
Language:
En
Journal:
Journal of Southern Medical University
Year:
2013
Type:
Article