Sildenafil citrate for erectile dysfunction in male kidney transplant recipients / 中华男科学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To evaluate the efficacy and safety of sildenafil citrate in man kidney transplant recipients with erectile dysfunction.</p><p><b>METHODS</b>One hundred and seventy married males, aged 26 approximately 50 years, who had received kidney transplantations at least half a year before and whose serum creatinine was under 133 umol/l, were selected randomly in the study. Their sexual function was investigated according to the International Index of Erectile Function-5 (IIEF-5), and those with erectile dysfunction (ED) were treated with oral sildenafil citrate for 6 months. The efficacy was assessed by IIEF-5.</p><p><b>RESULTS</b>Fifty-three men with ED received oral sildenafil citrate for 6 months. At the end of the treatment, each index in IIEF-5 increased significantly. There were no interactions between sildenafil and cyclosporine and there was no significant adverse effect of sildenafil on the graft function.</p><p><b>CONCLUSION</b>Sildenafil is an effective and safe agent for the treatment of ED in kidney transplant recipients.</p>