Chemical constituents of Psammosilene tunicoides and bacteriostatic activity / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study the chemical constituents and bacteriostatic activity of Psammosilene tunicoides.</p><p><b>METHOD</b>Such methods as silica gel column chromatography and gel column chromatography were adotped separate and purify the compounds, and their structures were indentified on the basis of their spectral data and physicochemical properties.</p><p><b>RESULT</b>Ten compounds were separated from ethanol extracts and identified as methyl-4-hydroxybenzoate (1), N-methylsaccharin (2), 3-hydroxy-4-methoxybenzoic acid (3), germanicol (4), tricosanoic acid (5), octacosane (6), amber acid (7), succinic acid (8), stellarine A (9), and oleanane-12-ene-3alpha, 16alpha-two hydroxy-23,28-acid (10).</p><p><b>CONCLUSION</b>All compounds except compound 10 were separated from P. tunicoides for the first time. Compounds 8 and 9 showed the bacteriostatic activity to a certain extent.</p>