The Adverse Effect of the 2-1-1 Regimen for Rabies PEP in Preschool Children / 生物医学与环境科学(英文)
Biomedical and Environmental Sciences
; (12): 373-375, 2017.
Article
in En
| WPRIM
| ID: wpr-311403
Responsible library:
WPRO
ABSTRACT
Post-exposure prophylaxis (PEP) has proved to be the most important measure for rabies prevention and control. There is little information regarding adverse reactions to the Essen and 2-1-1 regimens in preschool children (aged 0-6). We reexamined the outcomes of 1,109 preschool children who were vaccinated using SPEEDA under the Essen regimen between January 2011 and December 2012 and 1,267 preschool children under the 2-1-1 regimen between January 2013 and December 2014. We find that, in preschool children, the febrile reaction after the first 2-dose injection in the 2-1-1 regimen was significantly higher than that induced by the first 1-dose in the Essen procedure. Thus, we recommend that the Essen regimen should still be used for rabies PEP in preschool children.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Rabies
/
Reference Standards
/
Rabies Vaccines
/
Vaccination
/
Post-Exposure Prophylaxis
/
Germany
Limits:
Child
/
Child, preschool
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Humans
/
Infant
Country/Region as subject:
Europa
Language:
En
Journal:
Biomedical and Environmental Sciences
Year:
2017
Type:
Article