Correlation analysis of magnetic resonance imaging characteristics and intrahepatic recurrence of small hepatocellular carcinoma after radiofrequency ablation / 中华肝脏病杂志
Chinese Journal of Hepatology
; (12): 680-685, 2014.
Article
in Zh
| WPRIM
| ID: wpr-313970
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the correlation between magnetic resonance imaging (MRI) characteristics and intrahepatic recurrence of small hepatocellular carcinoma (HCC) after radiofrequency ablation (RFA).</p><p><b>METHODS</b>A total of 34 patients with 39 small HCC who underwent RFA were included in our study.MRI characteristics were compared between the recurrence group and the non-recurrence group; and a subgroup comparison was also made between the solitary recurrence group and the multiple recurrence group.Kaplan-Meier test,t-test/Mann-Whitney U test,Fisher's exact test and F-test were used for statistical analyses.</p><p><b>RESULTS</b>The median follow-up period was 25 (4-45) months and recurrence was observed in 19 (55.9%) of the patients.The 12-and 24-month cumulative recurrence-free survival rates were 71.3% and 51.8%,respectively.The recurrence group had a higher prevalence of lack of tumour capsule before RFA (P =0.017),no or disrupted periablational enhancement within 24 hours after RFA (P =0.012),and a smaller ablative margin (P=0.037).Meanwhile,the average apparent diffusion coefficient value within 24 hours after RFA was higher in the multiple recurrence group (1.57 * 10-3mm2/s) than in the solitary recurrence group (1.34 * 10(-3) mm2/s) (P =0.04).</p><p><b>CONCLUSION</b>MRI can provide early noninvasive findings useful for advanced warning ofintrahepatic recurrence after RFA.</p>
Full text:
1
Index:
WPRIM
Main subject:
Pathology
/
Recurrence
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Magnetic Resonance Imaging
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Survival Rate
/
Retrospective Studies
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Treatment Outcome
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Catheter Ablation
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Carcinoma, Hepatocellular
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Kaplan-Meier Estimate
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Liver Neoplasms
Type of study:
Observational_studies
Limits:
Humans
Language:
Zh
Journal:
Chinese Journal of Hepatology
Year:
2014
Type:
Article