The treatment research of people with different types of HPV infection in sterile patients / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology
; (6): 227-229, 2010.
Article
in Zh
| WPRIM
| ID: wpr-316915
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>Explore the optimal treatment of infertility patients infected with different types of human papillomavirus (HPV).</p><p><b>METHODS</b>According to cervical pathology, cervical status and the procreate desire of the infertility patients, the 144 clinic cases of high-risk human papillomavirus infected infertile patients were divided into two gruoups: group with treatment and without treatment. Real-time quantitative fluorescent PCR (RT-PCR) has been employed, follow-up time is 6 months, to detect the HPV-DNA in the crevical exfoliated cells, to observe the negative conversion rate and pregnancy rate, and compare analyzed.</p><p><b>RESULTS</b>(1) In high-risk HPV infectors, the negative conversion rate of treatment group (56.67%) is higher than those in non-treatment group (50.00%); (2) The pregnancy rate of secondary high-risk HPV non-treatment group (50.00%) is higher than the treatment group. The pregnancy rate of primary high-risk HPV treatment group (31.67%) is higher than the non-treatment group (4.00%). (3) Negative conversion rate increases accordingly, on primary high-risk HPV infected groups with Leep, with single drug and with Leep combined with drug therapy. (4) The negative conversion rate and the pregnancy rate of primary high-risk HPV infected groups with surgical therapy is higher than the groups with drug therapy. Surgical + Drugs is better in the two surgical therapies.</p><p><b>CONCLUSION</b>Infertile patients should be routinely screened for cervical HPV. The primary high-risk cervical HPV infection is the etiology of infertility. Preferably, patients with primary high-risk HPV infection in cervical lesions is treated with Leep combined drugs.</p>
Full text:
1
Index:
WPRIM
Main subject:
Papillomaviridae
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Therapeutics
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Virology
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DNA, Viral
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Pharmaceutical Preparations
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Polymerase Chain Reaction
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Epidemiology
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Risk Factors
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Pregnancy Rate
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Papillomavirus Infections
Type of study:
Etiology_studies
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Risk_factors_studies
Limits:
Adult
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Female
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Humans
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Pregnancy
Language:
Zh
Journal:
Chinese Journal of Experimental and Clinical Virology
Year:
2010
Type:
Article