A cross-sectional study on serum uric acid level and the distribution of metabolic syndrome among Uigur, Han and Kazak prediabetic groups in Xinjiang / 中华流行病学杂志

ABSTRACT

Objective To explore thelevels of uric acid,blood pressure,serum lipid metabolic disorders and the distribution of obesity and metabolic syndrome (MS) among Uygur,Han and Kazak pre-diabetic groups in Xinjiang.Methods A cross-sectional study was conducted on 2053 Uygur residents,2219 Kazak residents and 2656 Han residents aged 30-80,all with prediabectic syndromes.The pre-dialectic patients were divided into three groups for analysis on metabolic features and inter-group comparisons.Results (1)In total,1934 pre-diabetic cases (28.3％) were diagnosed,with the highest prevalence (31.6％) seen in Uygurs and the lowest (25.5％) in Kazaks and medium (27.0％) in Hans.Data from the inter-group comparison showed statistically significant differences (P=0.00).(2) Prevalence of high LDL-C was 80.5％,with hyperuricemia as 30.3％ and MS as 58.3％,while the inter-group comparison did not show any statistically significant differences (P＞0.05).(3)Prevalence of pre-diabetic when combined with hypertension or earlier-stage hypertension,reached 88.0％,with the highest (96.8％) among Kazak group,85.1％ in Uygurs and 83.7％ in Han population.Data from the inter-group comparison showed statistically significant difference (x2 =59.959,P=0.00).(4)The overall prevalence of prediabectic,when combined with obesity was 35.4％,with 29.6％ in Han,36.8％ in Uygur and 41.0％ in Kazak groups.Data from the inter-group comparison showed statistically significant difference (x2=19.097,P=0.00).Conclusion According to results from this cross-sectional study regarding the metabolic features of Uygur,Kazak and Han prediabectic groups,differences were seen in the prevalence rates of pre-diabetic among Uygur,Kazak and Han ethnic groups,with the highest seen in Uygurs and the lowest in Kazaks.Hyperlipidemia,hypertension,hyperuricemia,MS and obesity were commonly seen in all the prediabectic groups,with the highest prevalence of hypertension seen in the Kazak group and the highest rate of obesity in Uygur group.