Chemical constituents of leaves of Psidium guajava / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 1024-1029, 2014.
Article
in Zh
| WPRIM
| ID: wpr-321373
Responsible library:
WPRO
ABSTRACT
To study the chemical constituents of the 95% ethanol extract of Psidium guajava. Compounds were separated by using a combination of various chromatographic methods including silica gel, D101 macroporous resin, ODS, Sephadex LH-20 and preparative HPLC. Their structures were elucidated by physicochemical properties and spectral data Eighteen compounds were isolated and identified as (+) -globulol (1), clovane-2beta, 9alpha-diol (2), 2beta-acetoxyclovan-9alpha-ol (3), (+) -caryolane-1 ,9beta-diol (4), ent-T-muurolol (5), clov-2-ene-9alpha-ol (6), isophytol (7), tamarixetin (8), gossypetin (9), quercetin (10), kaempferol (11), guajaverin (12), avicularin (13), chrysin 6-C-glucoside (14), 3'-O-methyl-3, 4-methylenedioxyellagic acid 4'-O-beta-D-glucopyranoside (15), p-hydroxy-benzoic acid (16), guavinoside A (17) and guavinoside B (18). Compounds 2-9 and 14-16 were isolated from this plant for the first time. The ethanol extract showed 61.3% inhibition against the proliferation of colon cancer cell line SW480.
Full text:
1
Index:
WPRIM
Main subject:
Organic Chemicals
/
Drugs, Chinese Herbal
/
Chemistry
/
Plant Leaves
/
Psidium
Language:
Zh
Journal:
China Journal of Chinese Materia Medica
Year:
2014
Type:
Article