Clinical study on effect of fluoxetine combined with Chinese medicine or tibetan drugs in treating senile depression in plateau district / 中国中西医结合杂志
Chinese Journal of Integrated Traditional and Western Medicine
; (12): 202-204, 2006.
Article
in Zh
| WPRIM
| ID: wpr-331722
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To compare the ettect and side-ettect of fluoxetine and combination of fluoxetine and Chinese or Tibetan medicine in treating senile depression in plateau district. Methods Ninety patients with diagnosis of senile depression conformed to CCMD-3 standard, in plateau district of 2260 - 3200 m altitude were randomly divided into three groups and treated with fluoxetine (group A), fluoxetine plus Sanpu Xinnao Xin granule (group B) and fluoxetine plus Xiaoyao pill (group C), respectively, 30 cases in each group. Therapeutic effects were evaluated with Hamilton' s depressive scale (HAMD) and treatment emergent symptom scale (TESS) after 6 weeks treatment.</p><p><b>RESULTS</b>There was no significant difference in the therapeutic effects between the three groups. The adverse reaction in Group B and C was less than that in Group A (P<0.01). Conclusion Sanpu Xinnao Xin granule and Xiaoyao pill can raise the tolerance of patients with senile depression in plateau area against the adverse reaction of fluoxetine.</p>
Full text:
1
Index:
WPRIM
Main subject:
Drugs, Chinese Herbal
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Fluoxetine
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Selective Serotonin Reuptake Inhibitors
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Antidepressive Agents, Second-Generation
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Therapeutic Uses
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Depressive Disorder
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Drug Therapy
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Drug Therapy, Combination
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Altitude
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Phytotherapy
Limits:
Aged
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Humans
Language:
Zh
Journal:
Chinese Journal of Integrated Traditional and Western Medicine
Year:
2006
Type:
Article