Research progress of protein tyrosine phosphatase SHP-2 / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
; (6): 581-585, 2012.
Article
in Zh
| WPRIM
| ID: wpr-336748
Responsible library:
WPRO
ABSTRACT
The Src homology-2 domain-containing phosphatase SHP-2 encoded by PTPN11 is an essential component in several signaling pathways.Different types of mutation in SHP-2 have been confirmed in several types of leukemia and solid tumors. Elucidation of the events underlying Shp2-evoked transformation may provide new insights into the novel targets for anti-cancer therapy.
Full text:
1
Index:
WPRIM
Main subject:
Physiology
/
Chemistry
/
Protein Tyrosine Phosphatase, Non-Receptor Type 11
/
Metabolism
Limits:
Humans
Language:
Zh
Journal:
Journal of Zhejiang University. Medical sciences
Year:
2012
Type:
Article