Inflammatory reaction and alterations of pulmonary surfactant in Pseudomonas Aeruginosa pneumonia in immunocompromised rats / 中华医学杂志(英文版)
Chinese Medical Journal
; (24): 1099-1100, 2002.
Article
in En
| WPRIM
| ID: wpr-340375
Responsible library:
WPRO
ABSTRACT
Pulmonary surfactant ( PS ) compromises lipids and surfactant proteins (SP) and lines on the alveolar air-liquid interface. It can reduce surface tension, prevent alveoli from collapse and reduce alveoli edema by disaturated dipalmitoylphosphatidylcholine. It also modulates the pulmonary immunology by SP-A and SP-D. In this study,we established a rat model of immunocompromised host (ICH) with pulmonary infection of Pseudomonas aeruginosa (P. aeruginosa), then studied its pulmonary inflammatory reaction and analyzed the concentration of lipids and SP-A in bronchoalveolar lavage fluid (BALF) during infection.
Full text:
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Index:
WPRIM
Main subject:
Physiology
/
Proteolipids
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Pseudomonas Infections
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Pulmonary Surfactants
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Bronchoalveolar Lavage Fluid
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Chemistry
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Rats, Sprague-Dawley
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Pneumonia, Bacterial
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Pulmonary Surfactant-Associated Protein A
/
Pulmonary Surfactant-Associated Proteins
Limits:
Animals
Language:
En
Journal:
Chinese Medical Journal
Year:
2002
Type:
Article