Anti-LW Showing Anti-D Mimicking Specificity: A Case Report / 대한수혈학회지
Korean Journal of Blood Transfusion
; : 77-81, 2017.
Article
in Ko
| WPRIM
| ID: wpr-34205
Responsible library:
WPRO
ABSTRACT
LW antigens are expressed in higher intensities in D-positive blood cells than D-negative cells, which can result in false identification of anti-D in pretransfusion testing. Although several cases of anti-LW have been reported abroad, to the best of our knowledge, none have been reported in Korea. Herein, we report a case of anti-LW in a 58 year-old RhD positive patient with non-Hodgkin's lymphoma with a positive direct Coombs test and a suspicion of the presence of passive anti-D antibodies because of a history of intravenous immunoglobulin administration. However, during a 5-month follow up, the antibody was confirmed as anti-LW on grounds that it showed weakened reaction in dithiothreitol treated cells and enforced reaction in cord O+ cells when compared to the results from antibody identification panel cells.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Blood Cells
/
Lymphoma, Non-Hodgkin
/
Immunoglobulins
/
Coombs Test
/
Follow-Up Studies
/
Sensitivity and Specificity
/
Dithiothreitol
/
Korea
/
Antibodies
Type of study:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
Limits:
Humans
Country/Region as subject:
Asia
Language:
Ko
Journal:
Korean Journal of Blood Transfusion
Year:
2017
Type:
Article