Advances in the study of nitric oxide-donating drugs

Yi-hua ZHANG; Si-xun PENG

Advances in the study of nitric oxide-donating drugs / 药学学报

Yi-hua ZHANG; Si-xun PENG.

Acta Pharmaceutica Sinica ; (12): 1200-1210, 2009.

Article in Chinese | WPRIM | ID: wpr-344093

ABSTRACT

ABSTRACT

Nitric oxide (NO) as a messenger and/or effector plays important roles in vivo. The decreased availability of NO or dysfunction in NO signaling has often been implicated in the development and progression of diseases, and design and research of NO-donating drugs has become one of the important strategies in drug discovery. In connection with authors' scientific practice, this article reviews the recent advances in the research of NO-donating drugs.

Subject(s)

Animals; Humans; Anti-Inflammatory Agents, Non-Steroidal; Therapeutic Uses; Antineoplastic Agents; Pharmacology; Therapeutic Uses; Aspirin; Pharmacology; Therapeutic Uses; Azo Compounds; Pharmacology; Cardiovascular Diseases; Drug Therapy; Cell Line, Tumor; Drug Design; Neoplasms; Drug Therapy; Pathology; Nitrates; Pharmacology; Therapeutic Uses; Nitric Oxide; Metabolism; Nitric Oxide Donors; Pharmacology; Therapeutic Uses; Piperazines; Pharmacology; Signal Transduction

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Full text: Available Index: WPRIM (Western Pacific) Main subject: Pathology / Pharmacology / Piperazines / Azo Compounds / Cardiovascular Diseases / Drug Design / Signal Transduction / Anti-Inflammatory Agents, Non-Steroidal / Aspirin / Nitric Oxide Donors Limits: Animals / Humans Language: Chinese Journal: Acta Pharmaceutica Sinica Year: 2009 Type: Article

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