Neuroimaging of Hemichorea-Hemiballism
Journal of the Korean Neurological Association
; : 318-323, 2007.
Article
in Ko
| WPRIM
| ID: wpr-34780
Responsible library:
WPRO
ABSTRACT
BACKGROUND:
Hemichorea-Hemiballism (HCHB) can be caused by various diseases such as cerebrovascular disease, hyperglycemia, tumor, and inflammatory diseases. However, there are a few case studies using functional imaging such as single photon emission computed tomography (SPECT).METHODS:
In this study, we included patients with HCHB. The patients with hyperglycemia over 250 mg/dl or high signal intensity on T1 weighted imaging were excluded. Clinical and neuroimaging characteristics of the patients were obtained and analyzed.RESULTS:
We included 20 patients (MF=128, mean age=67.1+/-15.3). Sixteen patients were presented with hemiballism and four with hemichorea. Six patients had no structural lesions causing HCHB. Subthalamic nucleus was the causative lesion in 6 patients. Other lesions associated with HCHB were basal ganglia, thalamus, and cortices. In a patient without structural lesion, anti-double stranded DNA antibody was detected. Brain SPECT showed not only perfusion abnormalities in the cases without structural lesions but also additional abnormalities in those with definite lesions.CONCLUSIONS:
Various mechanisms were related to the development of HCHB. Functional imaging such as SPECT and immunological work-up is needed to investigate the underlying pathomechanism of HCHB.Key words
Full text:
1
Index:
WPRIM
Main subject:
Perfusion
/
Thalamus
/
Basal Ganglia
/
Brain
/
DNA
/
Tomography, Emission-Computed, Single-Photon
/
Subthalamic Nucleus
/
Dyskinesias
/
Neuroimaging
/
Hyperglycemia
Limits:
Humans
Language:
Ko
Journal:
Journal of the Korean Neurological Association
Year:
2007
Type:
Article