Acute Lymphoblastic Leukemia in Elderly Patients: A Single Institution's Experience
The Korean Journal of Internal Medicine
;
: 328-339, 2011.
Article
in English
| WPRIM
| ID: wpr-35155
ABSTRACT
BACKGROUND/AIMS:
We investigated the clinical characteristics and prognosis of elderly patients with acute lymphoblastic leukemia (ALL).METHODS:
We reviewed the clinical data, laboratory findings, bone marrow findings, and cytogenetic analysis of elderly patients (> or = 60 years) with ALL, and data of an additional 101 younger adult patients ( or = 60 years) and 101 younger adult patients ( or = 60 years) was 10.3 months (p = 0.003). In the elderly patients with ALL, T cell lineage and the presence of lymphadenopathy were significant prognostic factors for OS in a univariate analysis (p = 0.033 and 0.041, respectively).CONCLUSIONS:
The outcomes of Korean elderly patients with ALL were poor, and the shorter OS was mainly due to the low CR rate. T-cell lineage and the presence of lymphadenopathy were significant prognostic factors in Korean elderly patients with ALL.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Time Factors
/
Bone Marrow Examination
/
Remission Induction
/
Philadelphia Chromosome
/
Chi-Square Distribution
/
Logistic Models
/
Proportional Hazards Models
/
Survival Rate
/
Retrospective Studies
/
Risk Factors
Type of study:
Etiology study
/
Observational study
/
Prognostic study
/
Risk factors
Limits:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
Country/Region as subject:
Asia
Language:
English
Journal:
The Korean Journal of Internal Medicine
Year:
2011
Type:
Article
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