Studies on lignan glycosides from the roots of Bupleurum scorzonerifolium / 药学学报
Acta Pharmaceutica Sinica
; (12): 428-431, 2005.
Article
in Zh
| WPRIM
| ID: wpr-353442
Responsible library:
WPRO
ABSTRACT
<p><b>AIM</b>To study the lignan glycosides from the roots of Bupleurum scorzonerifolium. Chromatography methods was used to isolate compounds and chemical and spectral methods were used to identify the structures of isolated compounds.</p><p><b>RESULTS</b>Two lignan glycosides were isolated from the roots of B. scorzonerifolium and their structures were identified as 2, 3-E-2,3-dihydro-2-(3'-methoxy-4'-O-beta-D-glucopyranosyl-phenyl)-3-hydroxymethyl-5-(3"-hydroxypropenyl )-7-methoxy-1-benzo [b] furan (1) and 2, 3-E-2, 3-dihydro-2-( 3'-methoxy-4'-hydroxy-phenyl)-3-hydroxymethyl-5-( 3"-hydroxypropenyl)-7-O-beta-D-glucopyranosyl-1-benzo[b]furan (2), both of them which were the mixture of (+)2S,3R- and (-)2R,3S-type diastereoisomer and in both of them the amount of (+)2S,3R-type was a little more than that of the (-)2R,3S-type.</p><p><b>CONCLUSION</b>Compounds 1 and 2 were isolated from B. scorzonerifolium for the first time. (+)2S, 3R-2, 3-Dihydro-2-(3'-methoxy-4'-hydroxy-phenyl)-3-hydroxymethyl-5-(3"-hydroxypropenyl)-7-O-beta-D-glucopyranosyl-1-benzo[b] furan is a new compound.</p>
Full text:
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Index:
WPRIM
Main subject:
Plants, Medicinal
/
Chemistry
/
Lignans
/
Plant Roots
/
Bupleurum
/
Glycosides
/
Molecular Conformation
Type of study:
Prognostic_studies
Language:
Zh
Journal:
Acta Pharmaceutica Sinica
Year:
2005
Type:
Article