HOXB gene family and functions of hematopoietic stem/progenitor cells--review / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 343-347, 2005.
Article
in Chinese
| WPRIM
| ID: wpr-356562
ABSTRACT
Recently, many researches indicated the important role played by homeobox (HOX) gene family in normal hematopoiesis. As a kind of transcription factors, HOX gene products regulate and control the expression of target genes by binding to special DNA sequences. HOXB, a member of HOX gene family, especially HOXB(4), interests people greatly. It has been found that its expression relates closely to the self-renewal of hematopoietic stem cells and effective proliferation of hematopoietic progenitor cells. This review presents some new research progress in this area.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Physiology
/
Hematopoietic Stem Cells
/
Multigene Family
/
Homeodomain Proteins
/
Cell Biology
/
Allergy and Immunology
/
Genetics
/
Hematopoiesis
/
Metabolism
Limits:
Animals
/
Humans
Language:
Chinese
Journal:
Journal of Experimental Hematology
Year:
2005
Type:
Article
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