Cardiac Surgery in a Patient with Idiopathic Thrombocytopenic Purpura : Preoperative High-Dose Immunoglobulin Therapy / 日本心臓血管外科学会雑誌
Japanese Journal of Cardiovascular Surgery
; : 108-111, 2008.
Article
in Ja
| WPRIM
| ID: wpr-361803
Responsible library:
WPRO
ABSTRACT
A 62-year-old woman with idiopathic thrombocytopenic purpura (ITP) was admitted to undergo cardiac surgery for aortic stenosis, angina pectoris, and paroxysmal atrial fibrillation. A bleeding tendency was expected due to the dramatic decrease in platelets during cardiopulmonary bypass. We performed high-dose transvenous gammaglobulin infusion (400mg/kg/day) for 5 consecutive days immediately before surgery. The gammaglobulin therapy caused steady increase of thrombocytes from 4 days after surgery, even though the platelet count showed no significant change preoperatively. The postoperative course was satisfactory with neither a bleeding tendency nor wound infection. High-dose transvenous gammaglobulin therapy is thus useful for perioperative patients with accompanying ITP, who are often under medication with steroids. This therapy is also effective for prevention of infection.
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WPRIM
Language:
Ja
Journal:
Japanese Journal of Cardiovascular Surgery
Year:
2008
Type:
Article