ANGIOTENSIN I CONVERTING ENZYME GENE INSERTION/DELETION POLYMORPHISM AND HUMAN PHYSICAL PERFORMANCE / 体力科学
Japanese Journal of Physical Fitness and Sports Medicine
; : 527-532, 2008.
Article
in Ja
| WPRIM
| ID: wpr-362478
Responsible library:
WPRO
ABSTRACT
Angiotensin I converting enzyme (ACE) gene Insertion/Deletion (I/D) polymorphism was first shown as a genetic factor which influences human physical performance in 1998. Since then, various gene polymorphisms which influence physical performance and trainability have been reported. ACE is a key enzyme which produces angiotensin II in the renin-angiotensin system, and its activity was determined by I/D polymorphism. Many studies indicate that the I/I genotype is frequently found in elite endurance athletes, while the D/D genotype is frequently found in power-oriented elite athletes. Longitudinal studies show that the D/D genotype may contribute to enhanced strength trainability. However, it is still unclear whether the I/I genotype enhances endurance trainability. Therefore, the ACE gene I/D polymorphism can be a genetic factor which influences human physical performance.
Full text:
1
Index:
WPRIM
Type of study:
Observational_studies
Language:
Ja
Journal:
Japanese Journal of Physical Fitness and Sports Medicine
Year:
2008
Type:
Article