An Investigation into the Relief of the Pain Accompanying with Colonoscopy with Shakuyaku-kanzo-to / 日本東洋医学雑誌

ABSTRACT

In order to relieve the pain accompanying colonoscopy, we gave patients “Tsumura Shakuyaku-kanzo-to extract” 5.0g 30 minutes before their examination, and investigated its effect.<br>We were unable to find a statistical difference in the increase in systolic blood pressure and heart rate during the examination between the group prescribed Shakuyaku-kanzo-to (n=18) and the control group (n=20). However, the mean for visual pain score, by which we estimated the pain, was 4.89±0.42 in the group prescribed Shakuyaku-kanzo-to and 6.20±0.34 in the control group. This difference was statistically significant.<br>These results suggest that Shakuyaku-kanzo-to is effective as a premedication for relieving the pain accompanying colonoscopy. From the literature, we assume that this is caused mainly by the sedative effect resulting from suppression of the nerve center.