The Effects of Coenzyme Q10 on Oral Immunity and Health-Related Quality of Life in Middle-Aged and Elderly Individuals / 日本補完代替医療学会誌
Japanese Journal of Complementary and Alternative Medicine
; : 37-43, 2015.
Article
in Ja
| WPRIM
| ID: wpr-376393
Responsible library:
WPRO
ABSTRACT
<b>Objective:
</b> The purpose of this study was to examine the effects of Coenzyme Q10 (CoQ10) supplementation on salivary secretory immunoglobulin A (SIgA) and health-related Quality of Life (QOL) in middle-aged and elderly individuals. <b>Methods:
</b> Sixty healthy middle-aged and elderly individuals were assigned randomly to a CoQ10 supplementation group (n = 30) or a placebo supplementation group (n = 30) using a double blind method. Subjects took 150 mg CoQ10 or placebo per day for 8 weeks. Salivary SIgA secretion rate and SF-36 test (physical and mental health-related QOL) were determined before and after the intervention. <b>Results:
</b> CoQ10 group showed that a tendency to increase of salivary SIgA secretion rate (p = 0.08), although placebo group did not show significant change. Physical health-related QOL did not significantly change in both groups. Vitality and mental health scores, which were subscale of mental health-related QOL, were significantly increased after the intervention in CoQ10 group (p < 0.05), although placebo group did not show significant change. <b>Conclusion:
</b> 8 weeks of CoQ10 supplementation may bolster SIgA-mediated oral immunity and mental health-related QOL in middle-aged and elderly individuals.
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Index:
WPRIM
Type of study:
Clinical_trials
Language:
Ja
Journal:
Japanese Journal of Complementary and Alternative Medicine
Year:
2015
Type:
Article