Progress of zebrafish applied to kidney research / 国际儿科学杂志

ABSTRACT

As a kind of new model organisms,zebrafish attracts more and more scientists'attention.Because the nephrogenesis and much of kidney disease in zebrafish are similar to those in mammalian,many genes in both kidneys are conserved,and zebrafish has the more simple pronephron,which is convenient to operation and observation.The fish pronephron has been generally applied to study the development and disease of mammalian kidney.This review will focus on recent progress in applying the zebrafish pronephrons to issues of human health and development.