Effect of IL-2 to dendritic cell in chronic hepatitis B / 中国医师杂志
Journal of Chinese Physician
; (12): 1066-1068, 2008.
Article
in Zh
| WPRIM
| ID: wpr-398596
Responsible library:
WPRO
ABSTRACT
Objective To evaluate the role of IL-2 dendritic cell in chronic hepatitis B,peri-dendritic cells were cultured,cytokins CD4O,CD86,CD80,CD83 and IL-2 were measured by ELLISA.Methods 20 chronic hepatitis B patients were selected,each one donated 15ml blood.dentritic cells were cultured,and IL-4 1000u/ml rhGM-CSF 1000u/ml was given each well,while IL-2 100u/ml was given each control well.CD40,CD86,CD80 and CD83 were measured by FLSC at 9th day.IL-2 was detected by ELISA at 12th day.Results The level of CD40,CD86,CD80 and CD83 in increased when using IL-2,and dentritic cell secreted IL-2 in chronic hepatitis.Conclusion The results suggest that IL-2 can promote the phenotypic and functional maturation of PC.
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WPRIM
Language:
Zh
Journal:
Journal of Chinese Physician
Year:
2008
Type:
Article