The effects of early medical intervention on prognosis of newborn hypoxic -ischemic encephalopathy / 中国组织工程研究

ABSTRACT

ObjectiveTo detect the effects of early medical intervention on prognosis of newborn Hypoxic - ischemic encephalopathy (HIE) . Methods62 severe to moderate HIE newborns were randomly divided into intervention group(34 cases) and control group(28 cases ). The intervention group accepted trentment when they are newborn. Sexes, mothers' educational backgrond, enviroment and family incomewere similar for 2 groups. At the age of 6, 12, and 18 months, the assessment and mental development were conducted in two groups. ResultsThe development quotient(DQ) of the intervention group was higher than that of the control group( t = 2.3166, 2. 7298, 2. 8377, P ＜ 0. 05, ＜0. 01, ＜ 0. 01 ). The intervention group had higher rate of recovery and lower rate of unfavourble prognosis(x2 = 4. 1 031, P ＜ 0.05). ConclusionEarly continue intervention could promote the mental motor development, improve the prognosis, reduce the rate of the sequela and improvequality of life.