Ischaemia preconditioning attenuates hypothermic ischaemia-reperfusion related early graft dysfunction following orthotopic lung transplantation in the rat / 吉林大学学报(医学版)
Journal of Jilin University(Medicine Edition)
; (6): 162-165, 2000.
Article
in Zh
| WPRIM
| ID: wpr-412352
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ABSTRACT
Objective:To investigate the effect of ischaemia preconditioning (IP) on function of the transplanted lungs.Methods:Rat orthotopic left lung transplantation (OLT) was performed using the cuff anastomosis technique.The rats were divided into two groups ① CONT (n=16):OLT without IP.② IP (n=15):OLT plus IP.Results:In IP group blood gas exchange and recipient survivals were significantly improved and extravascular water content decreased compared with CONT group.Conclusion:Ischaemia preconditioning not only ameliorates graft injury but inhibits graft dysfunction after OLT.
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Language:
Zh
Journal:
Journal of Jilin University(Medicine Edition)
Year:
2000
Type:
Article