Effect of Total Flavonoids of Hippophae Rhamnoides on Contractile Mechanics and Calcium Transfer in Stretched Myocyte / 航天医学与医学工程
Space Medicine & Medical Engineering
;
(6): 6-9, 2000.
Article
in Chinese
| WPRIM
| ID: wpr-412788
ABSTRACT
Objective To study the role of total flavonoids of hippophae rhamnoides in improving contactile function of stretched cardiac myocyte.Method Flavonoids were given to stretched myocytes which were proved their contractile function decline and then myocyte contractile mechanics characteristics and calcium transfer were measured.Result Flavonoids increased myocyte contractility,as indicated by myocyte shortening,velocity of shortening,peak+dL/dt and peak-dL/dt during shortening,in a concentration-dependent manner (r>0.9,P<0.001),and with no relation to the intracellular calcium transfer in the myocytes.Conclusion Flavonoids of the traditional Chinese drug hippophae rhamnoids is effective in improving the contractile function of stretched cardiac myocyte in low dosage.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Space Medicine & Medical Engineering
Year:
2000
Type:
Article
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