The clinical efficacy and safety of intravenous cefmetazole in treatment of 1522 patients with aspiration pneumonia / 中华内科杂志
Chinese Journal of Internal Medicine
; (12): 295-298, 2011.
Article
in Zh
| WPRIM
| ID: wpr-413827
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WPRO
ABSTRACT
Objective To evaluate the efficacy and safety of intravenous cefmetazole in the treatment of patients with aspiratory pneumonia. Methods A multicenter, prospective and open-labeled trial was conducted. A total of 1522 patients were enrolled at the beginning, and only 1324 were evaluabled at the endpoint. The duration of treatment was 7-14 days. During the treatment and follow-up periods, we recorded any unexpected symptoms and abnormal laboratory tests. At last,we evaluated its efficacy and safety. Results The total effective rate of cefmetazole was 79. 8% (1056/1324). The total bacterial eradication rate was 75.0% ( 342/456 ) . The bacterial eradication rates of klebsiellar pneumonia, escherichia, staphyloccocus aureus and anaerobic bacteria were 78.2% (97/124), 80.8% (80/99), 89.0% (81/91), 9/11,respectively. Conclusions Cefmetazole is effective and safe in the treatment of aspiratory pneumonia.
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WPRIM
Language:
Zh
Journal:
Chinese Journal of Internal Medicine
Year:
2011
Type:
Article