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The correlation between PTH, Vitamin D and bone mineral density in elderly man with type 2-diabetes / 中国综合临床
Clinical Medicine of China ; (12): 143-145, 2012.
Article in Chinese | WPRIM | ID: wpr-417988
ABSTRACT
Objective To explore the impact of calciotropic hormones,such as parathyroid hormone (PTH)and vitamin D,on bone mineral density(BMD)in the old men with type 2-Diabetes.Methods Sixty elderly men with type 2-Diabetes were submitted to dual-energy X-ray absorptiometry to evaluate the BMD at lumbar spine and hip.Fasting blood samples were collected to evaluate the indexes of bone metablism and blood glucose.PTH and 25-(OH)-Vitamin D3 were measured and analyzed for their correlation with BMD at different sites.Results In all patients,the percentage of osteoporosis and osteopenia accounted for 20.0% and 53.3% of the patients according to BMD at lumbar or hip.Compared with the patient group with normal BMD,serum PTH was significantly higher in the patient group with osteopenia or osteoporsis([44.87 ± 10.62]μg/L vs[36.96 ±12.36]μg/L,P < 0.05 ;[50.24 ± 20.32]μg/L vs[36.96 ± 12.36]μg/L,P < 0.05).But there was no difference in 25-(OH)-Vitamin D3 levels between all groups.PTH was correlated negatively with BMD at hip (r =-0.224,P < 0.05),but not significantly correlated with BMD at lumbar(r =-0.187,P > 0.05)Conclusions Serum PTH was correlated negatively with BMD at hip in elderly man with type 2-Diabetes.

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Clinical Medicine of China Year: 2012 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Clinical Medicine of China Year: 2012 Type: Article