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Epidemiologic study of the distribution of urate crystals in patients with gout by foot dual-energy CT / 中华风湿病学杂志
Chinese Journal of Rheumatology ; (12): 556-559, 2012.
Article in Chinese | WPRIM | ID: wpr-427575
ABSTRACT
Objective To investigate the distribution of urate crystal as well as the relationship bet ween the features of the crystals and the attacks of joint pain and/or swollen by foot dual-energy CT.Methods Eight-four patients (68 were diagnosed as gout, 11 were patients with hyperuricemia and 5 were diagnosed as other types of arthritis) who recently experienced foot swelling and/or pain were enrolled and all of them were performed foot dual-energy CT.The relationship between the features of the urate crystals and the attacks of gouty arthritis was determined by Chi test and the potential risk factors were identified by Logistic multiple regression analysis.Results Two hundred and seventyeight urate crystal depositions were found in 68 gout patients,and the most common deposition sites were the distal parts of the first toe(18.2%),the first metatarso-phalangeal joint ( 16.8% ),calcaneus ( 17.5% ),the lower end of tibia ( 11.8% ).Furthermore,patients with the urate crystals deposited in the first metatrasophalangeal joint or the lower end of of tibia were more likely to experience acute episodes of gout attack (P<0.01,P<0.05 respectively).In addition,the shape,size and quantity of urate crystals also affected episodes of acute attack of gout.Conclusion Dual-energy CT,which is a non-invasive method,could clearly reveal urate crystal depositions and is helpful for the diagnosis and follow-up of patients with gout.The location,shape,size and quantity of urate crystals and soft tissue swelling,bone erosion may affect the acute attack of gout.

Full text: Available Index: WPRIM (Western Pacific) Type of study: Prognostic study / Risk factors Language: Chinese Journal: Chinese Journal of Rheumatology Year: 2012 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Type of study: Prognostic study / Risk factors Language: Chinese Journal: Chinese Journal of Rheumatology Year: 2012 Type: Article