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Detection of five periodontal pathogens in coronary atherosclerotic plaque / 中华微生物学和免疫学杂志
Article in Chinese | WPRIM | ID: wpr-428218
Responsible library: WPRO
ABSTRACT
ObjectiveTo detect five periodontal pathogenic bacteria in coronary atherosclerotic plaques.MethodsAtherosclerotic plaque specimens were obtained from 101 patients who scheduled for coronary artery bypass graft surgery.The bacteria DNA was obtained from coronary atherosclerotic plaques using the chelex-100 method.The extracted DNA were examined by PCR.ResultsWithin the 101 pieces of atherosclerotic plaque samples Porphyromonas gingivalis( Pg,31% ),Tannerella forsythensis(Tf,42% ),Prevotella intermedia( Pi,26% ),Fusobacterium nucleatum( Fn,21% ),Actinobacillus actinomycetemcomitans( Aa,23% ).PCR products were sequenced and were compared with GenBank sequences,the homology was 99%-100%.ConclusionPeriodontitis might affect the development of atherosclerosis and there is a correlation between coronary heart disease and chronic periodontitis.

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Microbiology and Immunology Year: 2011 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Chinese Journal of Microbiology and Immunology Year: 2011 Type: Article