Quality evaluations for five published meta-analyses of intravenous fish oil interventions on clinical outcomes by a measurement tool to assess systematic reviews / 中华临床营养杂志

ABSTRACT

Objective To use a measurement tool to assess systematic reviews (AMSTAR) to assess the methodological quality of published meta-analyses of intravenous fish oil interventions on clinical outcomes in postoperative or intensive care unit (ICU) patients supported with parenteral nutrition (PN).Methods PubMed,EMBASE,Cochrane Library,Web of Science,Chinese Biomedical Databases,China National Knowledge Infrastructure,Wanfang Database,and some other databases were searched to retrieve the eligible studies published from January 1996 to September 2013,and the relevant journals and the references of included studies were also retrieved manually.The studies were included if they were systematic reviews or meta-analyses that evaluated the effects of fish oil-enriched PN and standard PN for postoperative or ICU patients on clinical outcome.Two reviewers screened the literature according to the inclusion criteria and extracted the data.Then the AMSTAR was used to evaluate the quality of the included studies.Results A total of five relevant meta analyses were included.Based on AMSTAR,two studies were of high quality,one of moderate quality,and the other two were of low quality.Conclusions The methodological quality of these five published metaanalyses of intravenous fish oil interventions is uneven.Further large-scale and high-quality randomized controlled trials about the impact of intravenous fish oil on clinical outcomes and cost-effectiveness analysis for postoperative and ICU patients are needed.