Meta-analysis of the safety of Yangzhengxiaoji capsule for the treatment of cancer and precancerosis / 中国肿瘤临床
Chinese Journal of Clinical Oncology
;
(24): 1318-1323, 2013.
Article
in Chinese
| WPRIM
| ID: wpr-440747
ABSTRACT
Objective:
To evaluate the safety of Yangzhengxiaoji capsules for the treatment of cancer and precancerosis.Methods:
Clinical trials and studies were collected by searching Chinese and English databases, including CNKI, WANFANG database, VIP information database, Pubmed, ScinenceDirect Online, and MEDLINE@EBSCO. The clinical data of Yangzhengxiaoji capsule for the treatment of cancer and pre-cancerosis were included. The quality of the included studies was then evaluated. Related data were extracted with reference to Cochrane Handbook 5.0. Afterward, meta-analysis was conducted using Revman 5.0 software.Results:
A total of 19 studies focusing on 2 125 patients receiving Yangzhengxiaoji capsules were included and investigated in this meta-analysis. Results showed that the adverse reaction rates of myelosuppression, WBC and platelet decrease, gastrointestinal reaction, nausea/vomiting, and hepatotoxicity were sig-nificantly lower in the trial groups with Yangzhengxiaoji capsule-assisted chemotherapy/radiotherapy than in the control groups with chemotherapy/radiotherapy only (P0.05).Conclusion:
Yangzhengxiaoji capsule could be safely administered to treat cancer and precancerosis.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Systematic reviews
Language:
Chinese
Journal:
Chinese Journal of Clinical Oncology
Year:
2013
Type:
Article
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