Intestinal microbiota and neonatal necrotizing enterocolitis / 国际儿科学杂志

ABSTRACT

The intestinal microbiota is composed of beneficial bacteria and harmful bacteria in the body as the ecological environment,which is the largest,most complex microecosystem.There is emerging evidence that appropriate colonization process of intestinal microbes contributes to development of intestinal structure and function and maturation of immune system,which determines the risk of intestinal diseases.More and more studies focus on the relationship between intestinal microecology or probiotics and neonatal necrotizing enterocolitis (NEC).This article reviews the composition and function of neonatal intestinal microbiota,the intestinal microflora in the pathogenesis and mechanism of NEC and preventive effects of probiotics on NEC.