Risk factors of pancreatic fistula after pancreaticoduodenectomy / 中华消化外科杂志
Chinese Journal of Digestive Surgery
; (12): 531-534, 2014.
Article
in Zh
| WPRIM
| ID: wpr-450968
Responsible library:
WPRO
ABSTRACT
Objective To investigate the risk factors of pancreatic fistula after pancreaticoduodenectomy.Methods The clinical data of 310 patients who received pancreaticoduodenectomy at the Ruijin Hospital of Shanghai Jiaotong University from January 2005 to May 2013 were retrospectively analyzed.The risk factors associated with the interoperative pancreatic fistula were analyzed.The univariate and multivariate analysis were done using the Pearson chi-square test and non-conditional Logistic regression model.Results A total of 134 patients had postoperative complications,including 103 (33.23%) with pancreatic fistula,among them 40 patients developed additional complications.The results of univariate analysis showed that preoperative levels of hemoglobin,total bilirubin,diameter of the pancreatic duct and postoperative level of albumin were risk factors of pancreatic fistula after pancreaticoduodenectomy (x2 = 4.543,6.087,6.265,5.311,P < 0.05).The results of multivariate analysis showed that preoperative level of total bilirubin equal to or above 34.2 μmol/L,the diameter of the pancreatic duct under 3 mm and the level of postoperative albumin under 28 g/L were the independent risk factors of pancreatic fistula (OR =1.806,1.936,1.780; 95% confidence interval1.107-2.948,1.170-3.206,1.002-3.165,P < 0.05).Conclusion Preoperative jaundice (the level of total bilirubin ≥ 34.2 umol/L),pancreatic duct diameter < 3 mm and postoperative malnutrition (albumin < 28 g/L) indicate a higher incidence of postoperative pancreatic fistula.
Full text:
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Index:
WPRIM
Type of study:
Etiology_studies
/
Prognostic_studies
/
Risk_factors_studies
Language:
Zh
Journal:
Chinese Journal of Digestive Surgery
Year:
2014
Type:
Article