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The association between Fas-670 gene polymorphisms and clinic pathologic index of breast cancer in Qinghai district / 重庆医学
Chongqing Medicine ; (36): 2617-2619, 2014.
Article in Zh | WPRIM | ID: wpr-453092
Responsible library: WPRO
ABSTRACT
Objective To investigate the correlation between Fas-670 gene polymorphisms and the clinic pathologic index of breast cancer in Qinghai district .Methods The polymorphisms of Fas-670 gene were detected by polymerase chain reaction-restric-tion fragment length polymorphisms assay (PCR-RFLP) in 232 female breast cancer patients ,χ2 test was applied to assess the asso-ciation between the polymorphisms of Fas-670 gene and breast cancer clinic pathologic index .Results In 232 breast cancer pa-tients ,the frequency of Fas-670 homozygous wild type(AA) ,heterozygous type(AG) ,homozygous mutant type(GG) were 39 .7%(92/232) ,48 .7% (113/232) ,11 .6% (27/232) respectively .It was no statistical significance between Fas-670 gene polymorphisms and the clinic pathologic index of breast cancer in Qinghai district(P>0 .05) .Conclusion The polymorphisms of Fas-670 gene is not associated with clinic pathologic index of breast cancer in Qinghai district .
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Full text: 1 Index: WPRIM Language: Zh Journal: Chongqing Medicine Year: 2014 Type: Article
Full text: 1 Index: WPRIM Language: Zh Journal: Chongqing Medicine Year: 2014 Type: Article