Optimization of Preparation Technology of Compound Sodium Lactate Injections for Improvement of Clar-ity / 中国药师
China Pharmacist
;
(12): 348-349, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-461059
ABSTRACT
Objective:
To optimize the preparation technology of compound sodium lactate injections for the improvement of clari-ty.Methods:
The orthogonal test was adopted to screen the best preparation conditions using four influencing factors including the de-carburization temperature of the concentrated solution (A), pH value of the concentrated solution (B), decarburization time of the concentrated solution ( C) and the filling temperature of the injections ( D) with 3 levels for each, and the clarity of the injections as the index.Results:
The best preparation conditions were as followsthe decarburization temperature was 60℃, pH value of the con-centrated solution was 6. 5, the decarburization time was 20minute and the filling temperature was 50℃.Conclusion:
The optimal process can improve the clarity of compound sodium lactate injections.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacist
Year:
2015
Type:
Article
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