Evaluation of the efficacy of botulinum toxin type A in the treatment of trigeminal neuralgia / 实用口腔医学杂志
Journal of Practical Stomatology
; (6): 401-406, 2015.
Article
in Zh
| WPRIM
| ID: wpr-463576
Responsible library:
WPRO
ABSTRACT
Objective:To review the clinical efficacy of botulinum toxin type A(BTX-A)in the treatment of trigeminal neuralgia (TN).Methods:The main bibliographic databases were searched from English and Chinese literatures on the topic and the refer-ences of the identified articles were also searched for additional studies.2 reviewers assessed the quality of the included studies and extracted data duplicate.Results:3 Chinese and 1 English reports with 203 participants were included.However,substantial hetero-geneity(I2 =77%)precluded meta-analysis and the results were individually described.3 trials reported that BTX-A was more effec-tive than the control and 1 showed no difference between groups.Adverse effects of BTX-A were reported in 4 reports and were mild to moderate.Conclusion:BTX-A is effective in treating TN with few adverse effects.However,the evidence is weak because of a few studies included and most of them with low methodological quality.Further studies with high quality are needed to testify the evidence.
Full text:
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Index:
WPRIM
Language:
Zh
Journal:
Journal of Practical Stomatology
Year:
2015
Type:
Article