Effects of Acupuncture at Acupoint Neiguan (PC 6) and Intravenous Injection of Larginine on the Improvement of Acute Myocardial Ischemia / 针灸推拿医学(英文版)
Journal of Acupuncture and Tuina Science
; (6): 136-139, 2006.
Article
in Zh
| WPRIM
| ID: wpr-471717
Responsible library:
WPRO
ABSTRACT
Objective:
The present study is to observe and compare the different effects of electroacupuncture(EA) at acupoint Neiguan (PC 6), intravenous administration of L-arginine(L-Arg, a precursor of nitric oxide), and the drug administration combined with the EA on acute myocardial ischemia(AMI) in rats.Methods:
The rat model of AMI was established by occlusion of the anterior descending branch of the left coronary artery, then the animals were divided randomly into 5 groups,i.e. control group, AMI group, L-Arg treatment group, EA treatment group and L-Arg plus EA treatment group, the mean arterial pressure(MAP), heart rate(HR) and the cardiac functions were observed and recorded.Results:
The data showed that MAP, HR and all the indices of cardiac functions in the AMI group were significantly lower than those in control group, and the indices in each treatment group were all improved to different extents, especially in L-Arg plus EA treatment group.Conclusion:
The combined use of L-Arg and EA had the better therapeutic effect on the AMI.
Full text:
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Index:
WPRIM
Language:
Zh
Journal:
Journal of Acupuncture and Tuina Science
Year:
2006
Type:
Article