MicroRNAs and atherosclerosis / 国际脑血管病杂志
International Journal of Cerebrovascular Diseases
; (12): 637-640, 2015.
Article
in Zh
| WPRIM
| ID: wpr-480479
Responsible library:
WPRO
ABSTRACT
Atherosclerosis is the most important cause of ischemic stroke. microRNAs can play an important role in the lipid metabolism, vascular inflammatory response, angiogenesis, as wel as smooth muscle cel proliferation and phenotypic conversion, etc. by regulating the functions of vascular endothelial cel s, vascular smooth muscle cel s, and mononuclear macrophages. It is closely associated with the occurrence and development of atherosclerosis. This article mainly reviews the regulatory effect of microRNAs on lipid metabolism and vascular inflammatory response in pathogenesis of atherosclerosis.
Full text:
1
Index:
WPRIM
Language:
Zh
Journal:
International Journal of Cerebrovascular Diseases
Year:
2015
Type:
Article