Analysis on iron metabolism indicators in children with various genotypes of thalassemia / 国际检验医学杂志
International Journal of Laboratory Medicine
; (12): 2947-2949, 2015.
Article
in Zh
| WPRIM
| ID: wpr-482005
Responsible library:
WPRO
ABSTRACT
Objective To study the value of iron metabolism indicatorsin thalassemia .Methods 218 cases of thalassemia ,57 ca‐ses of iron deficiency anemia (IDA) children and 70 healthy children(control group) were enrolled in the study ,and serum iron (SI) ,total iron binding capacity(TIBC) ,transferrin(Tf) ,serum ferritin (SF) were detected for them .Results β‐thalassemia double heterozygous(β0 ) or homozygous group :SI levels were significantly higher than the other groups(P0 .05) ,but Tf level was higher than control group(P0 .05) .Conclusion Compared with Tf ,SI and TIBC are better indicators for monitoring iron loading in children with thalassemia .The increased SI level and decreased TIBC level are two indicators for the diagnosis of β0 thalassemia in children with cellule anaemia .
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Index:
WPRIM
Language:
Zh
Journal:
International Journal of Laboratory Medicine
Year:
2015
Type:
Article