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Composing and evaluating the measurement uncertainty of two kinds of chemiluminescence detection system / 中华核医学与分子影像杂志
Article in Zh | WPRIM | ID: wpr-489263
Responsible library: WPRO
ABSTRACT
Objective To compose and evaluate the measurement uncertainty of two kinds of chemiluminescence detection system using different methods.Methods The measurement uncertainty was composed by 4 different

methods:

(1) U 1% was composed of within-run CV(CVw %),between-run CV(CVB %)and bias (CVBias %);(2) U2% was composed of CVB % and uncertainty of calibration (CVcal %);(3) U3% was composed of CVW%,CVs% and CVcal%;(4) U4% was composed of CVW%,CVB%,CVBias% and CVcal%.The measurement uncertainty of Architect i2000SR system (Abbott,USA) and DXI800 system (Beckman,USA) was assessed.Pearson correlation analysis,Spearman correlation analysis,Paried t test and Mann-Whitney u test were performed to analyze the data.Results For Architect i2000SR system,U1%,U2%,U3% and U4% were significantly correlated (r=0.727-0.988,all P<0.05),U3% and U2% were significantly different (t =6.88,P<0.05),U4% and U1% were significantly different (t =6.21,P<0.05).For DXI800 system,U1%,U2%,U3% and U4% were also significantly correlated (r =0.608-0.975,all P<0.05),no significant difference was found between U3% and U2% (z=-1.33,P>0.05),or between U4% and U 1% (z =-1.04,P> 0.05);the expanded measurement uncertainty was correlated with CVW%,CVB%,CVBias%(rs=0.653-0.912,all P<0.05),but not with CVcal%(rs=0.548,P>0.05).Conclusions For Architect i2000SR system,the fourth method is more proper to compose the measurement uncertainty (U4%).For DXI800 system,the first method is more appropriate (U1%).According to the contribution of different components to the measurement uncertainty,the measurement quality could be improved by reducing the imprecision and bias.
Key words
Full text: 1 Index: WPRIM Type of study: Diagnostic_studies Language: Zh Journal: Chinese Journal of Nuclear Medicine and Molecular Imaging Year: 2016 Type: Article
Full text: 1 Index: WPRIM Type of study: Diagnostic_studies Language: Zh Journal: Chinese Journal of Nuclear Medicine and Molecular Imaging Year: 2016 Type: Article