Evaluation of markers and perfusion parameters in donated liver quality during machine perfusion / 中华肝胆外科杂志
Chinese Journal of Hepatobiliary Surgery
; (12): 63-67, 2017.
Article
in Zh
| WPRIM
| ID: wpr-506032
Responsible library:
WPRO
ABSTRACT
Liver transplantation has become the most effective treatment option for end-stage liver diseases.The liver donation after cardiac death (DCD) had been increasingly used in clinical practice.Nevertheless,the DCD donated livers inevitably exposed to long-term ischemia and hypoxia makes the implanted organs with decreased function and more postoperative complications.Different from the conventional static cold storage,machine perfusion (MP) can be continuously used in vitro liver perfusion,which could simulate the in vivo liver status.Through the observation of ischemia injury status,we could evaluate the quality of donated liver,and thus reduce ischemia related complications.This review provides an overview and evaluation on the markers that have been investigated for the assessment of graft quality and viability testing during different types of MP.
Full text:
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Index:
WPRIM
Language:
Zh
Journal:
Chinese Journal of Hepatobiliary Surgery
Year:
2017
Type:
Article