Safety Assessments for Human Skin Fibroblasts Cultured in Vitro / 中国医师杂志
Journal of Chinese Physician
; (12)2000.
Article
in Zh
| WPRIM
| ID: wpr-519904
Responsible library:
WPRO
ABSTRACT
Objective Conduct safety assessments of the established human skin fibroblast line. Methods A series of safety assessments were performed including cell morphology,chromosome karyotyping,soft-agar test,nude mice carcinogenic test,endotoxin test,mycoplasma determination,detection of viral agent,bacteria,fungi sterile tests and abnormal toxicity test.Results No abnormal changes were observed.Conclusion The fibroblast obtained from skin is a kind of safety and reliable target cell for gene therapy.
Full text:
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Index:
WPRIM
Language:
Zh
Journal:
Journal of Chinese Physician
Year:
2000
Type:
Article