Determination of Metformin Hydrochloride in Compound Metformin Hydrochloride Tablets by UV-Spectrophotometry / 中国药房
China Pharmacy
; (12)2001.
Article
in Zh
| WPRIM
| ID: wpr-524961
Responsible library:
WPRO
ABSTRACT
OBJECTIVE:
To establish UV-spectrophotometry method in the determination of metformin hydrochloride in compound metformin hydrochloride tablets.METHODS:
The determination was carried out with water as the solvent under the detection wavelength of233nm.RESULTS:
There was a good linear relationship between metformin hydrochloride and its absorbability(r=0.9999)within the concentration range of1~10?g/ml.The average recovery was99.3%with RSD at0.24%(n=9).CONCLUSION:
The method is accurate,fast,convenient,and which can be used to determine the contents of metformin hydrochloride in compound metformin hydrochloride tablets directly without isolation.
Full text:
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Index:
WPRIM
Language:
Zh
Journal:
China Pharmacy
Year:
2001
Type:
Article