Determination of the Content of Menthol in Inclusion Complex of Compound Essential Oil-? -cyclodextrin by GC-MS / 中国药房
China Pharmacy
; (12)2005.
Article
in Zh
| WPRIM
| ID: wpr-529260
Responsible library:
WPRO
ABSTRACT
OBJECTIVE: To establish GC-MS method for the determination of the Menthol in inclusion complex of compound essential oil-? -cyclodextrin. METHODS: Menthol was determined with ion fragment peak ( M/Z=71) . The chromatographic column was DM-5 fused silica capillary column ( 0. 25mm? 30m) ; the internal standard was naphthol and the temperature programming was 80~ 180℃ . RESULTS: The calibration curves of Menthol were linear in the ranges of 1. 344~ 10. 752? g? mL-1( r=0. 999 8) and the average recovery was 97. 52% , RSD=1. 56% . CONCLUSION: The method is rapid, accurate and reproducible, and suitable for the quality control of the same kind of the preparation.
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Index:
WPRIM
Language:
Zh
Journal:
China Pharmacy
Year:
2005
Type:
Article