Specific coalescent peptides binding with CD59 on HeLa cells screened by phage peptide library / 中国免疫学杂志
Chinese Journal of Immunology
; (12)1986.
Article
in Zh
| WPRIM
| ID: wpr-544865
Responsible library:
WPRO
ABSTRACT
Objective:To search for carrier of short active peptide with binding to human CD59 of the surface of HeLa cell.Methods:Ph. D. 12 display peptide library was biopanning with HeLa cell high-expressing CD59. After competitive test, positive phage clones were identified by sandwich ELISA and sequenced.Results:10 phage clones were identified to have higher combination with CD59.Conclusion:The sequence of peptide with binding to CD59 has been obtained.That might lay a basis for design of short peptide of CD59 on tumor sneaking through.
Full text:
1
Index:
WPRIM
Language:
Zh
Journal:
Chinese Journal of Immunology
Year:
1986
Type:
Article